My mom has 46% carbon monoxide in her blood from smoking... is this too much?

Not to discount the information you are giving us... but first check the decimal of that level. The way CO(carbon monoxide) measurement works is that the blood test (if thats how they t4ested it, because there are other ways to go about it) tells you the percent of Hemoglobin (the sites on the blood cells that carry oxygen, carbon dioxide or carbon monoxide) that is saturated with CO. That means that is your mom has 46% saturated by Co then 54% is left to carry oxygen and CO2. If someone suffering from smoke inhalation (like that from a fire) has a Co level of 10 percent they are likely to has some serious symptoms and if they are closer to 50% they are likely to be unconscious or having a seizure. A normal non smokers level of CO is usually less than 1% and a smokers level is usually in the 2-4% range. So from my end it would make much more sense to expect your mom to have a level of 4.6% rather than 46%... 46 is a really high number. Half the CO in your system leaves your body in 4-6 hours too so for your mom too be able to keep a level of 46% would take a lot of cigarettes to keep up with... if it really is 46% i dont know what to tell you because that is really high. If its 4.6% then thats not too far off from normal.